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中文摘要：
经过近三年的研究工作, 研究群体圆满完成了研究计划，实现了预计各项科学目标，在生命分析化学的新原理、新方法、人类疾病相关基因和蛋白质的识别与传感、新药代谢机制与药理研究等方面取得了具有自主知识产权的系列研究成果，建立了有特色的生命分析化学研究平台，并产生了国际影响。这些成果丰富和发展了分析化学基本原理和相关学科的内涵，为生命科学研究、临床诊断、新药开发、卫生防疫与监督、食品安全和其它突发事件等的分析检测提供了新的技术与有力工具。研究成果发表论文242篇（SCI论文238篇）(其中IF>3.0刊物178篇； >5.0刊物65篇，>7.0刊物13篇，包括J. Am. Chem. Soc. 1篇, Nano Lett. 1篇, Adv. Mater. 1篇, Adv. Funct. Mater. 10篇, Anal. Chem. 18篇，Clin. Cancer Res. 1篇 申请发明专利27件、实用新型专利1件、国际专利1件，授权专利16件。出版专著1部，合著专著1部（科学出版社），合编英文专著1部，中文专章2章、英文专章5章，获国家自然科学二等奖1项，省部级奖4项。
成果综合统计
期刊论文
会议论文
专利
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著作
期刊论文
A disposable two-throughput electrochemical immunosensor chip for simultaneous multianalyte determin
Channel-resolved multianalyte immunosensing system for flow-through chemiluminescent detection of α-
Selective detection of glucose with wide concentration range by bienzyme channeling based on co-entr
Functional mutilwalled carbon nanotube nanocomposite with iron picket-fence porphyrin and its electr
Ultrasonic-assisted size-controllable synthesis of Bi2Te3 nanoflakes with electrogenerated chemilumi
Triterpenoids from Cimicifugae rhizoma, a novel class of inhibitors on bone resorption and ovariecto
Hemoglobin on phosphonic acid terminated self-assembled monolayers at gold electrode: immobilization
Enhanced solid-state electrochemilumi- nescence of CdS nanocrystals composited with carbon nanotubes
Enzyme-quantum dots architecture for highly sensitive electrochemilumines- cence biosensing of oxida
Highly Efficient and Selective Enrichment of Phosphopeptides Using Porous Anodic Alumina Membrane fo
Theoretical investigations of the geometric and electronic structures of phenylene-acetylene macrocy
Length-Dependent Conductance of Molecular Wiresand Contact Resistance in Metal–Molecule–Metal Juncti
Synthesis, characterization and immobilization of Prussian blue modified Au nanoparticles:applicatio
Synergistic effect of Prussian blue grafted carbon nanotubes/poly(4-vinylpyridine) composites for se
Template-Synthesized Protein Macroporous Biofilms Electrode: Conformational Related Electron Transfe
Characterization of plant growth-promoting rhizobacteria using capillary isoelectric focusing with w
Simultaneous determination of etamsylate, tramadol and lidocaine in human urine by capillary electro
Highly resolved separation and sensitive amperometric detection of amino acids with a flexible micro
Small molecules-controlled spontaneous growth of Se crystals with roselike and orchidslike shapes at
Luminescence and defect studies of Ce3+ doped CaS phosphor synthesized via solid state diffusion met
Luminescence and EPR investigations of Mn activated calcium aluminate prepared via combustion method
Theoretical investigation on conformational behavior of 2,2’-bithiophene under the influence of exte
First-principles study of substituents effect on molecular junctions: Towards molecular rectificatio
Determination of polymerization retarder 4-hydroxyanisole in triallyl cyanurate for industrial use b
Determination of silymarin flavonoids by HPLC and LC-MS, and investigation of extraction rate of sil
Three-Dimensionally Ordered Macroporous Gold Structure as an efficient matrix for Solid State Electr
Glucose microfluidic biosensors based on immobilizing glucose oxidase in poly(dimethylsiloxane) elec
Off-line form of the Michaelis-Menten equation for studying the enzyme kinetics in a polymer microch
Indirect amperometric measurement of electroosmotic flow rates and effective mobilities in microchip
Synthesis of functional polypyrrole/prussian blue and polypyrrole/Ag composite microtubes by using a
Ordered mesoporous polyaniline film as a new matrix for enzyme immobilization and biosensor construc
Hb-CdTe-CaCO3@Polyelectrolytes 3D Architecture: Fabrication, Characteri- zation and Application in B
Synthesis, photoluminescence, thermoluminescence and electron spin resonance investigations of CaAl1
Theoretical investigations of oligo(phenylene ethylene) molecular wire: effects from substituents an
Sonochemical synthesis and resonance light scattering effect of Zn(II)bis(1-(2-pyridylazo)-2-naphtho
Direct electron transfer and biosensing application of proteins immobilized on NaY zeolite and mesop
Coupling imaging mode to investigate the electric field distribution at the end-channel of capillary
A Simple Electrochemical Method for the Detection of Hydroxyl Free Radicals without Separation Proce
Zirconia nanoparticles enhanced grafted collagen tri-helix scaffolds for unmediated biosensing of hy
Luminescent CdS nanochains templated on unfixed DNA and their fractal alignment by droplet dewetting
Flow-through multianalyte chemiluminescent immunosensing system with designed substrate zone-resolve
Dynamic kinetic capillary isoelectric focusing: a powerful tool for studying protein-DNA interaction
Aminopolycarboxyl-modified Ag2S nanoparticles: Synthesis, characterization and resonance light scatt
Antimony(III)-doped PbWO4 crystals with enhanced photoluminescence via a shape-controlled sonochemic
Silver/silver oxide-silicon dioxide nanoparticles modified electrodes for electrochemical sensing of
Determination of heterocyclic amines by capillary electrophoresis with UV-DAD detection using on-lin
Sonochemical route for self-assembled V2O5 bundles with spindle-like morphology and their novel appl
Ag/polypyrrole core-shell nanostructures: Interface polymerization, characterization, and modificati
Sampling-resolution strategy for one-way multiplexed immunoassay with sequential chemiluminescent de
Conductive mesocellular silicate- carbon nanocomposite foams for immobilization, direct electrochemi
Simultaneous determination of psychoactive drugs in human urine by capillary electrophoresis with el
A disposable and reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membra
A disposable multianalyte electrochemical immunosensors array for automated simultaneous determinati
Controllable synthesis of one-dimensional chinelike superstructures of homogeneous Bi100-xSbx alloys
Simultaneous electrochemilumines- cence detection of anisodamine, atropine and scopolamine in Flos D
Electrodeposition of silver-DNA hybrid nanoparticles for electrochemical sensing of hydrogen peroxid
A biocompatible conductive architecture of carbon nanofiber-doped chitosan prepared with controllabl
Electric field-driven strategy for fast multiplexed detection of protein biomarkers using a disposab
Highly sensitive amperometric determination of carbohydrates with a portable silicone/quartz capilla
Effective cell capture with tetrapeptide functionalized carbon nanotubes and dual signal amplificati
Coreactant enhanced anodic electrochemiluminescence of CdTe quantum dots at low potential for sensit
Preparation, luminescence and defect studies of Eu2+-activated strontium hexa-aluminate phosphor pre
High efficient separation and electrochemical detection of neurotransmitters on a native printed cap
Liquid chromatographic fingerprint of 3-methylflavone-8-carboxylic acid established for its synthesi
Novel C-Au ligand mechanism for the synthesis of super stable n-trimethyl chitosan chloride derivati
Direct electron transfer and electrocatalysis of hemoglobin adsorbed on mesoporous carbon through la
An unusual metabolite of cimicidol-3- O-β-D-xyloside from Cimicifugae rhizoma by rat intestinal bact
Nano-pit corrosion of the tabs in aluminum electrolytic capacitor: Polarization characteristics of t
Al2O3/SnO2 co-nanoparticle modified grafted collagen for improving thermal stability and infrared em
Direct electrochemistry and electrocatalysis of hemoglobin in gelatine film modified glassy carbon e
会议论文
Sonochemical synthesis of nanoparticles with spherical and 1D structures and fabrication of ectroche
Electrochemical identification of the property of peripheral nerve fiber Based on a Biocompatible po
Progress in analytical biochemistry- - -from electrochemical to luminescent techniques and from nano
Electrochemical assay of cell surface carbohydrates and electrochemiluminescence biosensing based on
SECM probing the electric field distribution at the end-channel of a microchip capillary electrophor
Intermolecular interactions of aromatic molecules with methyl-β-CD using quantitative 1H and 2D diff
Whole column imaging detection and related approaches: Are they applicable for doping control analys
Electrochemical Identification of the Property of Peripheral Nerve Fiber Based on a Biocompatible Po
Potential application of microfluidics in antidoping analysis applicable for doping control analysis
Flow-through multianalyte chemiluminescent immunosensing system for sequential detection of tumor ma
Some thoughts on the existence of ion and water channels in highly dense and well-ordered CH3-termin
Applications of nanoparticles in microchip channel modification and electroosmotic flow manipulation
The prediction of RP-HPLC retention behavior of monocarboxylic acids using acid as the ion-suppresso
Research of electrochemical immunosensor for identifying the property of peripheral nerve fiber rapi
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