目的:探讨大柴胡汤在临床的应用规律,从而更有效地指导临床应用。方法:全面检索中国生物医学文献数据库(CBM)、中国知网(CNKI)、维普中文科技期刊全文数据库(VIP)和万方医药期刊数据库(WF),对该方近三十年公开发表的期刊报道进行整理,按照Excel2007建立的信息采集表提取数据,建立临床研究文献疾病谱,对临床文献进行评价。结果:大柴胡汤共纳入1543篇文献。其中理论研究795篇、临床研究422篇、实验研究192篇、其他134篇。结论:大柴胡汤的高频系统病症集中在消化系统疾病,其高频病种分布在急性胆囊炎、急性胰腺炎等较为急性的病种。
Objective: To analyze the articles published in the past 30 years with the method of evidence- based medicine,in order to find out the clinical rules of the use of Major Bupleurum Decoction( DRBMM) and provide consultation for hereafter clinical use. Methods: Comprehensively search CBM,CNKI,WF and VIP to identify the maximum possible articles and establish the information database to extract data by using Excel 2007. Establish spectrum of diseases in clinic and Use evidence- based medicine technique for the clinical researches. As there was no standard for the assessment of single case reports,the Delphi method was used for formulating the quality standard of single case reports prescribed with DRBMM. Results: 1543 reviews were identified,including 795 theoretical researches,422 clinical researches,192 experimental studies and 134 other studies. Conclusion: The Major Bupleurum Decoction can mainly treat the digestive system diseases,especially the acute diseases such as the acute cholecystitis,acute pancreatitis and so on.