中文摘要：

目的 了解乌鲁木齐市吸毒人群首次共用器具注射毒品的发生情况及影响因素。方法 于2004年9～10月，应用结构式问卷调查乌鲁木齐市吸毒者社会人口学特征，首次吸毒、注射吸毒和首次共用注射器具时间。结果 509名吸毒者中，59．5％（303／509）曾经共用器具注射毒品。从首次吸毒到首次共用器具注射毒品的发生率为8．8／100人年（95％CI=7．819～9．810）。多因素Cox比例风险回归模型分析结果显示，首次吸毒年份（HR=1，654，95％CI=1．284～2，132）与共用器具注射吸毒发生率差异有统计学意义；从首次注射吸毒到首次共用器具注射毒品的发生率为18．4／100人年（95％CI=16．279～20．426）。多因素Cox比例风险回归模型分析结果显示，性别（HR=1．448，95％CI=1．129～1．858）与共用器具注射吸毒发生率差异有统计学意义。结论 乌鲁木齐市吸毒人群共用器具注射毒品发生率高．可能是当地艾滋病病毒感染者快速增长的原因之一。

英文摘要：

Objective To estimate the incidence of sharing injection equipment among drug users in Urumqi, Xinjiang. Methods During September to October 2004, a survey was conducted to collect demographic information including ethnicity, marital status, education, and employment status, initial drug use, initial injection drug use and first time of sharing injection equipment with other drug users among drug users. Results A total of 509 drug users were interviewed and 59.5 % （303/509） shared injection equipment in the past. The average incidence of sharing injection equipment was 8.8 per 100 person-years（95 % CI 7. 819-9. 810）from initial drug use to first sharing injection equipment, year of initial drug use（ HR = 1.654,95 % CI 1.284- 2.132） was independently associated with first sharing of injection equipment in the multivariate Cox proportional hazard regression model. The average incidence of sharing injection equipment was 18.4 per 100 personyears （95 % CI 16. 279-20. 426） from initial injecting drug to first sharing injection equipment, according to the multivariate Cox proportional hazard regression model, gender（ HR ： 1. 448, 95 % CI 1. 129 - 1. 858） was independently associated with first sharing injection equipment. Conclusion The average incidence of sharing injection equipment among drug users was high, which could contribute to the rapid transmission of HIV among drug users in Urumqi.