目的了解乌鲁木齐市静脉吸毒人群人类免疫缺陷病毒(HIV)相关危险行为状况及其影响因素。方法于2004年9~10月在乌鲁木齐市戒毒所、劳教所采用结构式问卷进行一次性横断面调查。结果符合调查标准且提供知情同意书的509名吸毒者中,近3个月共用器具注射吸毒比例为33.4%,固定性伴注射吸毒者占20.4%;近1个月与固定性伴和非固定性伴从未使用安全套的比例分别为85.8%和69.8%,维吾尔族吸毒者该指标的比例最高,分别为90.7%和75.3%。多因素线性回归分析结果显示,男性静脉吸毒者发生HIV相关危险行为的影响因素是固定性伴注射吸毒(β=0.80;P〈0.0001)、近6个月有商业性性行为(β=0.32;P=0.0135)、维吾尔族(β=0.34;P=0.0019)、已婚或同居者(β=-0.30;P=0.0077);与女性吸毒者有关的影响因素是固定性伴注射吸毒(β=0.36;P=0.0041)、近6个月有商业性性行为(β=0.45;P=0.0240)、年龄(β=-0.03;P=0.0154)。结论当地吸毒人群HIV相关危险行为发生率高。吸毒者与固定性伴的安全套使用率极低,提示HIV经性途径传播的可能性很大。扩大针对吸毒和高危性行为干预项目的覆盖面,并辅以个体化的心理咨询,加强吸毒者安全行为的健康教育。
Objective To know HIV risk behavior level and association among injecting drug users in Urumqi. Methods A cross-sectional study was conducted among drug users in center for detoxification from September to October, 2004. All participants underwent a structured interview including demographics, drug use characteristics and sexual behaviors before incarceration. Results A total of 509 participants met inclusion criteria and signed informed consent. 33.4% participants shared needles last 3 months. 20.4 % drug users had an IDU primary sex partner. Sexual intercourse with no condom with regular sex partner and casual sex partner was 85.8 % and 69.8 %, respectively, and it was 90.7 % and 75.3 % among Uigur drug users. Association with HIV risk behavior was analyzed using multiple regression model, having an IDU primary sex partner( β = 0.80 ; P 〈 0. 000 1 ), having commercial sexual behavior last 6 month( β = 0.32 ; P = 0. 013 5 ), Uigur people( β = 0.34;P =0.001 9) and being married or cohabiting(β = - 0.30; P = 0.007 7) for men;and having an IDU primary sex partner(β = 0.36;P = 0. 004 1 ), having commercial sexual behavior last 6 month(β = 0.45;P = 0. 024 0) and age(β = - 0.03;P = 0. 015 4) for female. Conclusion HIV risk behavior level was high among local drug users. Condom use was extremely low with primary sex partner, HIV will be transmitted by sexual behavior, and it should be focused. Enlarging target on drug use and high risk sexual behavior program and integrated with individual counseling in order to keep doing safe practice among drug users is necessary.