目的观察帕罗西汀联合电针经络氧与单用帕罗西汀治疗躯体形式障碍的临床疗效差别。方法68例躯体形式障碍患者随机分为研究组(帕罗西汀联合电针经络氧治疗)和对照组(单用帕罗西汀治疗)。于治疗前及治疗后第1、2、4周末用症状自评量表(SCL-90)躯体化因子分和汉密尔顿抑郁量表(HAMD)分评定疗效。结果治疗后两组SCL-90躯体化因子分、HAMD总分较治疗前明显较少,差异有显著性(P〈0.01);4周后,研究组有效率82.4%,对照组52.9%,差异有显著性(P〈0.01),从第一周末开始,研究组SCL-90中躯体化因子分即明显低于对照组(P〈0.05)、第2周末开始研究组HAMD总分亦明显低于对照组(P〈0.05)。结论帕罗西汀联合电针经络氧比单用帕罗西汀治疗躯体形式障碍起效更快、疗效更佳。
Objective To study the clinical effects of paroxetine combined with electricoacupuncture plus me- ridian oxygen in the treatment of somatoform disorders. Methods A total of 68 patients with somatoform disorder were randomly assigned to study group(paroxeine combined with electricoacupuncture plus meridian oxygen) and control group(single paroxetine)for the treatment of 4 weeks. They were assessed with the smatization factor of SCL-90 and HAMD before and 1st,2nd,4th weeken of the treatment. Results The factor scores of somatization in SCL--90 and total scores of HAMD in two groups were significantly decreased after the treatment,and there had significant differences between two groups(P〈0.01). At the end of 4th week, effective rates of study group and control group were 82.4 % and 52.9 % respectively, which had a significant difference (P〈0. 01). The factor somatization scores of in study group were significantly lower than those in control group at the end of lst,2nd and 4th week after treatment,and total scores of HAND in study group were also significantly lower than those in control group at the end of 2nd and 4th week (P〈0.05). Conclusion Paroxetine combined with electricoacupuncture plus meridian oxygen would take effects fast and have good efficacy in the treatment of somatoform disorders.