中文摘要：

瞄准：评估肝炎 B 的效果 colorectal 癌症的肝转移上的病毒(HBV ) 感染。方法：1298 个 colorectal 癌症病人的一个总数在这研究从 2001 年 1 月被招募到 2005 年 3 月。连接酶的 immunosorbent 试金被用来为 colorectal 癌症测试浆液 HBV 标记。病人们被划分成组和控制(非感染) 组织的学习(感染) 。在二个组的病人的临床的特征被比较。结果：肝转移从 1298 个 colorectal 癌症病人在 319 被发现。肝转移的发生比在控制组在学习组是显著地更低的(14.2% 对 28.2% ， P < 0.01 ) 。HBV 感染显著地减少了肝转移的风险[危险比率(HR ) ：0.50， 95% 信心间隔(95% CI ) ：0.38-0.66 ] ，但是 extrahepatic 转移的发生比在控制组在学习组是显著地更高的(31.9% 对 17.0% ， P < 0.01 ) 。HR 在长期的肝炎 B 组是最低的(HR：0.29， 95% CI：0.12-0.72 ) 。肝的数字变形损害少些显著地与更高外科的切除术率比在控制组在学习组织。然而，没有重要差别处于在二个组之间的幸存率被发现(P = 0.95 ) 。结论：HBV 感染减少在有 colorectal 癌症的病人的肝转移的风险并且提高肝的外科的切除术率变形损害。

英文摘要：

AIM：To evaluate the effect of hepatitis B virus （HBV） infection on liver metastasis of colorectal cancer.METHODS：A total of 1298 colorectal cancer patients were recruited from January 2001 to March 2005 in this study.Enzyme-linked immunosorbent assay was used to test serum HBV markers for colorectal cancer.Patients were divided into study （infection） group and control （non-infection） group.Clinical features of patients in two groups were compared.RESULTS：Liver metastasis was found in 319 out of the 1298 colorectal cancer patients.The incidence of liver metastasis was significantly lower in study group than in control group （14.2% vs 28.2%,P 0.01）.HBV infection significantly decreased the risk of liver metastasis [hazard ratio （HR）：0.50,95% confidence interval （95% CI）：0.38-0.66],but the incidence of extrahepatic metastasis was significantly higher in study group than in control group （31.9% vs 17.0%,P 0.01）.The HR was the lowest in chronic hepatitis B group （HR：0.29,95% CI：0.12-0.72）.The number of liver metastatic lesions was significantly less in study group than in control group with a higher surgical resection rate.However,no significant difference was found in survival rate between the two groups （P=0.95）.CONCLUSION：HBV infection decreases the risk of liver metastasis in patients with colorectal cancer and elevates the surgical resection rate of liver metastatic lesions.