中文摘要：

为了寻找新的含噻唑杂环的先导化合物，利用2-取代-1，3-噻唑烷1与氯甲酸取代苯基酯2及取代苯基甲酰氯4在三乙胺存在下发生缩合反应，合成了6个2-取代-1，3-噻唑烷-3-甲酸酯类化合物3和5个N-苯甲酰基-2-取代-1，3-噻唑烷类化合物5，并利用^1H NMR，IR，MS，元素分析对其结构进行了表征．用X-ray单晶衍射测定了2-硫代-1，3-噻唑烷-3-甲酸苯酯（3d）和M苯甲酰基-2-氧代-1，3-噻唑烷（5a）的晶体结构，证实了氯甲酸酯与2，硫代-1，3-噻唑烷的反应产物为硫酮式结构，而非硫酯式结构．初步生物活性试验结果表明，在试验浓度下部分目标化合物3和5具有一定的杀菌和杀虫活性．

英文摘要：

In order to find new thiazole-heterocycle lead compounds, six 2-oxo/thio-1,3-thiazolidine- 3-carboxylates 3 and five N-substituted benzoyl-2-oxo/thio-1,3-thiazolidines 5 were synthesized from a condensation reaction of 2-oxo/thio-1,3-thiazolidine I and substituted phenyl chloroformates 2 or substituted benzoyl chlorides 4 in presence of Et3N. Their structures were confLrmed by 1H NMR, IR, MS spectra and elemental analysis. The crystal structures of phenyl 2-thiono-1,3-thiazolidine-3-carboxylate （3d） and N-benzoyl-2-oxo-1,3-thiazolidine （5a） were determined by X-ray diffraction analysis, and the structure of the condensation products of 2-thiono-1,3-thiazolidine with substituted phenyl chloroformates was proved to be 2-thiono-1,3-thiazolidine-3-carboxylate rather than the ester of mercaptothiazoline. The preliminary bio- assay showed that compounds 3 and 5 exhibited certain fungicidal and insecticidal activities.