中文摘要：

目的：应用超声心动图评定雄性Balb／c小鼠的心脏形态和功能。方法：应用13MHz线控阵超声探头检测27只Balb／c雄性小鼠心脏（周龄：5—7周），超声检测后，进行戊巴比妥麻醉处死分离左室，测量湿重.结果：获得小鼠完整2维超声心动图，并记录雄性小鼠血流动力学参数：用M型超声心动图计算左室重量与左室湿重呈线性相关：y=1．15x＋3．26（r=0．80）。结论：超声心动图参数能够评定小鼠的心脏形态和功能。

英文摘要：

To assess the parameters of cardiac structure and function of male Balb/c mice by the eehocardiography. Methods： A total of 27 male Balb/c mice（from five to seven week old） were examined with a 13-MHz transthoracic linear-array transducer, hearts were removed from mice anesthetized with Butaylone, and the left ventricular（LV） mass were weighed. Results： Complete 2-dimensional echocardiography for cardiac structure and function were obtained. Hemodynamic parameters were recorded. A correlation existed between LV weight（x） and echocardiographic LV mass（y） with the 2D guided M-mode method： y = 1.15x ＋ 3.26, （ r = 0.80）. Conclusion： Echocardiography appears to be a promising approach for noninvasively assessing LV mass and function in mice.