目的:调查分析延边农村地区汉族和朝鲜族居民血脂异常分布特征。方法:调查于2004-08/09完成,随机抽取延边地区汪清县大兴沟镇汉族和朝鲜族居民455名,均自愿参加调查。排除混血民族。①按统一的调查表(包括研究对象的一般情况、心脑血管疾病的既往史及家族史等)进行家访询问调查。②测量身高、体质量、腰围、臀围、血压等。取清晨空腹静脉血,测量血清总胆固醇、三酰甘油、高密度脂蛋白胆固醇、空腹血糖等指标,均用全自动生化分析仪测定。③分析血脂异常与其影响因素的关系采用Logistic回归分析。结果:调查问卷、体格检查及生化指标检测结果完整者455人。①两民族血脂异常率比较:朝鲜族男女血脂异常率显著高于汉族[84.1%,88.8%;30.7%,42.1%(x^2=48.9,53.4,P〈0.01)],而且其高胆固醇血症、低高密度脂蛋白胆固醇血症、单纯高收缩压、单纯高舒张压、高血糖等患病率也均高于汉族(P〈0.05-0.01),朝鲜族女性的高三酰甘油血症患病率高于汉族女性(P〈0.01)。②血脂异常者不同血脂类型构成:延边农村地区的血脂异常以低高密度脂蛋白胆固醇为主要类型。③血脂异常相关因素的多因素分析:最终进入方程的因素分别为:民族、性别、收缩压、空腹血糖及腰围(OR=0.108,95%(21:0.061~0.190;OR=1.539,95%CI:0.970~2.441;OR=1.670.95%CI:1.020~2.757;OR=2.565.95%CI:270~5.183;OR=1.890,95%CI:1.196~3.008)。结论:延边农村地区汉族和朝鲜族人群血脂异常患病率存在差异,该地区的血脂异常与居民的民族、性别、收缩压、空腹血糖及腰围有关,并且以低高密度脂蛋白胆固醇血症为主要类型。
AIM: To investigate the distribution character of abnormal blood lipid in Han and Korean nationalities in urban of Yanbian area. METHODS: The investigation was performed from August to September 2004. Using simple randomized principle, 455 people of Han nationality and Korean-Chinese in the Daxinggou town, Wangqing county of Yanbian area were selected. They all agreed to join the survey voluntarily. Halfblood members were excluded. ①According to the unified questionnaire (contained general condition of testees, past history and family history of cardiovascular disease) home visit was done. ②Height, body mass, waistline, breechline and blood pressure, etc. were measured. Fasting abdominal vein was got. Serum total cholesterol, triacylglycerol, HDL cholesterol, fasting glucose, etc. were detected with full-auto biochemical analyzer. ③Abnormal blood lipid and its related factors were analyzed with Logistic regression analysis. RESULTS: Totally 455 persons were with complete questionnaire, physical examination and biochemical index.①Comparison of abnormal rate of blood lipid of the two nations: The abnormal rate of blood lipid in males and females of Korean nation was higher significantly than that in the Han nation [84.1% ,88.8% ;30.7% ,42.1%(x^2=48.9,53.4,P 〈 0.01)]. The prevalence rates of hypercholesterolemia, low and high density lipoprotein cholesterol, single high systolic pressure, single high diastolic pressure, high glucose, etc. were higher than those of Han nation (P 〈 0.05-0.01 ). The prevalence rate of triacylglycerol symptom in female of Korean was higher than that of Han nation (P 〈 0.01). ②Construction of different blood lipid type in abnormal blood lipid patients: Low and high density lipoprotein cholesterolemia was mainly in countryside of Yanbian area. ③ Multiple analysis of related abnormal blood lipid: Finally, the factors entered equation were nation, sex, systolic pressure, fasting glucose and waistline (OR=0.108, 95%CI:0.061-0.190; OR=1.539, 9