中文摘要：

随着接受麻醉的老年患者和阿尔采末病患者人数的增加，全身麻醉药物与阿尔采末病之间的关系日益受到医学和社会的关注。研究发现慢性术后认知功能障碍类似阿尔采末病，部分吸入麻醉药参与了阿尔采末病的病理机制。全麻原理、慢性术后认知功能障碍和阿尔采末病在对突触可塑性影响方面存在内在的联系。因此全身麻醉药物与阿尔采末病关系的研究也成为了麻醉学研究的热点之一。

英文摘要：

The relationships between general anesthetics and Alzheimer＇s disease （AD） have being widely concerned in medical care and society following the rapid increasing numbers of elderly patients and AD patients undergoing general anesthesia. Current researches show that postoperative cognitive dysfunction （POCD） is similar with AD, and some general anesthetics used in clinical practice are involved in the complicated mechanisms of AD, and the theory of general anesthesia, chronic POCD, and AD may share some unknown mechanisms in terms of the synaptic plasticity. Researches of the relationships between general anesthetics and AD become one of the central issues of anesthesia studying.