目的对光叶铁仔Myrsine stolonifera根和茎化学成分进行研究。方法运用D101型大孔吸附树脂、硅胶和凝胶Sephadex LH-20等柱色谱方法进行分离纯化,根据化合物的理化性质和波谱数据鉴定化合物结构。结果从光叶铁仔95%乙醇提取物中分离得到11个化合物,分别鉴定为山柰酚(1)、二氢山柰酚(2)、槲皮素(3)、5,7,4′-三羟基异黄酮(4)、柯伊利素(5)、槲皮素-7-O-α-D-葡萄糖苷(6)、表儿茶素(7)、3,5-二甲氧基-苄醇-4-O-β-D-吡喃葡萄糖苷(8)、2,6-二甲氧基-4-羟基-苯酚-1-O-β-D-吡喃葡萄糖苷(9)、丁香苷(10)、(+)-lyoniresino 3α-O-β-D-glucopyranoside(11)。结论化合物2、4-11首次从该属植物中分离得到,化合物1-11首次从该植物中分离得到。
Objective To study the chemical constituents from the radix and rhizome of Myrsine stolonifera. Methods The chemical constituents were isolated and purified by D101 macroporous adsorption resin, silica gel, and Sephadex LH-20 column chromatography. The structures of the isolated compounds were identified on the basis of physicochemical properties and spectroscopic methods including 1H-NMR, 13C-NMR, and MS spectra. Results Eleven compounds were identified as askaempferol(1), dihydrokaempferol(2), quercetin(3), 5, 7, 4′-trihydroxyisoflavone(4), chrysoeriol(5), quercetin-7-O-α-D-glucoside(6),(-)-epicatechin(7), 3, 5-dimethoxy-benzylalcohol-4-O-β-D-glucopyranoside(8), 2, 6-dimethoxy-4-hydroxyphenol-1-O-β-Dglucopyranoside(9), syringing(10), and(+)-lyoniresinol3α-O-β-D-glucopyranoside(11). Conclusion Compounds 2, 4—11 are all isolated from the plants of Myrsine Linn. for the first time, and compounds 1—11 are all isolated from this plant for the first time.