中文摘要：

目的研究苦杏仁、桔梗及两者配伍的止咳、祛痰作用,确定两者最佳配伍比例。方法分别采用浓氨水和枸橼酸刺激法制造小鼠和豚鼠咳嗽模型,记录咳嗽潜伏期和咳嗽次数;采用小鼠腹腔注射酚红、测定气管浸出液分光光度值法,研究小鼠气管排泌作用。结果苦杏仁、桔梗及两者不同配伍均有显著延长咳嗽潜伏期、减少咳嗽次数、促进气管排泌的作用;与单味苦杏仁或单味桔梗组比较,两者配伍组的上述作用有不同程度的增强。结论苦杏仁与桔梗配伍对止咳、祛痰有增效作用,两者配伍用于止咳、祛痰的最佳比例分别为1∶1和1∶2。

英文摘要：

AIM To study the proper rate of bitter apricot seed to platycodon root,in the treatment of relieving cough and expelling phlegm.METHODS Cough models were made by strong agua stimulation in mouse and citric acid stimulation in guinea pig,cough latency and cough times were recorded respectively.Model for expelling phlegm,phenol red solution was injected intraperitoneally to mice,and the spectroplcoto metric measurement of the trachea leachate was carried out.RESULTS Bitter apricot seed,platycodon root,and their different combinations all significantly reduced the cough times,prolonged the coughing latent period,and increased the trachea excretion.CONCLUSION The effect of relieving cough and expelling phlegm is the strongest when the compatibility ratio of bitter apricot seed and platycodon root is 1∶ 1 and 1∶ 2 respectively.