全氟烷酸类化合物是一类新型的持久性有机污染物,已被广泛应用于工业生产以及生活用品中,在全球各地的环境介质和人群中均检测到了该化合物的存在,该类化合物的环境健康效应已经引起了广泛的关注。本文对该化合物的特征、来源、毒代动力学特征、毒性效应以及相关的机制进行了总结,以进一步了解该化合物毒理学方面的研究进展。
Perfluoroalkyl acids (PFAAs) are an emerging persistent organic pollutant. With the wide application in industrial and general products, these compounds have been detected in the environmental matris and human population. The concerns about the effects of PFAAs on environment and health have been generated. This review summarizes the characteristics, source, toxicokinetics, toxic effects of PFAAs and related mechanisms for further understanding PFAAs progress in toxicology.