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耳蜗基底膜的力学仿真模型
  • 期刊名称:J South Med Univ
  • 时间:2014
  • 页码:79-83
  • 分类:R641.07[医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:[1]南方医科大学生物医学工程学院, [2]南方医科大学基础医学院,广东广州510515
  • 相关基金:国家自然科学基金(31171059,30970982);长江学者和创新团队发展计划(IRTl142)
  • 相关项目:听觉系统特异性与非特异性投射的相互作用及其突触微环路
中文摘要:

目的建立耳蜗基底膜的力学模型,验证基底膜特征频率和特征位置的关系。方法通过所建模型,采用宏观力学方法,简化模型细节,通过仿真工具对基底膜的振动和选频特性进行分析。结果耳蜗基底膜具有较明显的选频特陛,即基底膜上离镫骨较近段对高频敏感,离镫骨较远段对低频敏感。结论仿真结果显示,基底膜的选频特陛主要由基底膜的宽度等几何尺寸及其材料特f生沿纵向变化来实现,与耳蜗内螺旋器上其他微小组织关系不大。

英文摘要:

Objective To establish a mechanical simulation model for studying the relationship between the characteristic frequency and feature location of the basilar membrane of the cochlea. Methods Macro-mechanical methods were used to simplify the details of the model. With simulation tools, the basilar membrane vibration frequency characteristics were analyzed based on the box model. Results The basilar membrane had obvious frequency-selective properties, and the basilar membrane from the stapes was sensitive to high frequencies while the farther membrane was sensitive to low frequencies. Conclusion The frequency characteristics of the basilar membrane of the cochlea is mainly a result of the longitudinal variations of the geometric dimensions and material properties and is not related with other structures within the cochlea corti.

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