在这研究,我们调查了潜伏振幅(L-A ) 的特征在不同健全频率工作,用从在在老鼠的劣等的 colliculus (国际计算中心) 的中央原子核的听觉的神经原的细胞外的记录。从单个神经原的 Isofrequency L-A 功能能基于 Pierons 法律与一个最新发达的方程是合适的。健康的高度显示为一个给定的神经原的所有 isofrequency L-A 功能的弯曲是类似的,并且 L-A 之间的差别工作,这由于在他们在坐标系统的位置的移动。当我们使 L-A 函数正常化匹配时, L-A 函数的位置在 neuronal 特征频率(CF ) 获得了,从一个给定的国际计算中心神经原的所有 isofrequency L-A 函数高度被附加。在不同频率的 L-A 功能的类似的形状可以反映被变成 bioelectric 信号的声音的物理法律。一个 non-CF L-A 函数的位置能在象 CF 那样的引用频率与 L-A 函数相比作为 asymptotic L 和 A (L 和 A ) 的差别被测量。为声学的信息处理与一个神经原连接的神经纤维和触处能机能上地作为一根单个电线被简化(作为神经纤维的全部的长度) 并且关节(作为触处的 summated 尺寸 / 力量) 。电线和关节调停信息传播和 transduction 分别地。因此, L 和 A 可以是神经纤维的全部的长度和在激活的听觉的小径的 summated 触处的力量的大小。L 和 A 在频率隧道和神经原之间不同,建议声学的 neuronal 回答的差别被不同小径的激活总是引起,并且处理声音的小径是多样的。
In this study, we investigated the features of latency-amplitude (L-A) functions at different sound frequencies, using extracellular recording from auditory neurons in the central nucleus of the inferior colliculus (ICC) in mice. Isofrequency L-A functions from single neurons could be fit with a newly developed equation based on Pieron's law. The high degree of fitness indicates that the curvatures of all isofrequency L-A functions for a given neuron are similar, and that the difference between L-A functions is due to a shift in their positions in the coordinate system. When we normalized the L-A functions to match the position of the L-A function obtained at the neuronal characteristic frequency (CF), all isofrequency L-A functions from a given ICC neuron were highly su- perimposed. The similar shapes of the L-A functions at different frequencies may reflect the physical laws of sound being trans- ferred into bioelectric signals. The position of a non-CF L-A function could be measured as the differences of the asymptotic L and A (△L and △A) compared to the L-A function at a reference frequency such as the CF. The nerve fibers and synapses connect- ing to a neuron for acoustic information processing can be functionally simplified as a single "wire" (as the total length of nerve fibers) and "joint" (as the summated size/strength of synapses). The wire and joint mediate information transmission and trans- duction, respectively. Thus, △L and △A may be measurements of the total length of nerve fibers and the strength of summated synapses in the activated auditory pathway. △L and △A differed between frequency channels and neurons, suggesting that the dif- ferences of acoustic neuronal responses are always caused by activation of different pathways, and that the pathways that process sounds are diverse.