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Interactions between mycoplasma lipid-associated membrane proteins and the host cells
  • ISSN号:1673-1581
  • 期刊名称:《浙江大学学报:B卷英文版》
  • 时间:0
  • 分类:R37[医药卫生—病原生物学;医药卫生—基础医学]
  • 作者机构:[1]Institute of Pathogenic Biology, School of Medicine, Nanhua University, Hengyang 421001, China
  • 相关基金:Project (No. 30570093) supported by the National Natural Science Foundation of China.ACKN0WLEDGEMENT The authors wish to thank WAN Yan-ping and WANG Xin for their critical review of the manuscript, and thank Yi Chao-qun and WANG Ji-ping for their assistance with its preparation.
中文摘要:

Mycoplamas 是广泛地在自然散布的一组无墙的初核质,其中一些为人是病原的;动物。有许多脂蛋白在血浆膜的外部脸上抛锚了,叫的联系类脂化合物的膜蛋白质(灯) 。灯是高度反遗传因子;能经历阶段;尺寸变化,;被天生的免疫系统通过像使用费的受体(TLR ) 认出 2;6。灯能调制免疫系统,;能导致有免疫力的房间 apoptosis 或死亡。另外,他们可以与宿主细胞的恶意的转变联系;也被认为是在爱滋病的前进的余因子。

英文摘要:

Mycoplamas are a group of wall-less prokaryotes widely distributed in nature, some of which are pathogenic for humans and animals. There are many lipoproteins anchored on the outer face of the plasma membrane, called lipid-associated membrane proteins (LAMPs). LAMPs are highly antigenic and could undergo phase and size variation, and are recognized by the innate immune system through Toll-like receptors (TLR) 2 and 6, LAMPs can modulate the immune system, and could induce immune cells apoptosis or death. In addition, they may associate with malignant transformation of host cells and are also considered to be cofactors in the progression of AIDS.

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期刊信息
  • 《浙江大学学报:B卷英文版》
  • 中国科技核心期刊
  • 主管单位:
  • 主办单位:浙江大学
  • 主编:
  • 地址:杭州玉古路20号,浙江大学学报《英文版》编辑部
  • 邮编:310027
  • 邮箱:jzus@zju.edu.cn
  • 电话:0571-87952276 87952331
  • 国际标准刊号:ISSN:1673-1581
  • 国内统一刊号:ISSN:33-1356/Q
  • 邮发代号:
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:323