中文摘要：

基于微波辅助提取（MAE）中药材中化学成分的非稳态扩散过程，根据Fick第二定律建立了石蒜中石蒜碱、力可拉敏和加兰他敏以及虎杖中白藜芦醇和大黄素微波辅助提取过程的动力学模型。研究了提取时间、提取温度及药材粒度等因素对石蒜中石蒜碱、力可拉敏和加兰他敏以及虎杖中大黄素和白藜芦醇的提取率的影响，采用Matlab软件编程对动力学模型进行回归分析，拟合的动力学模型与实验结果吻合。根据模型计算了石蒜中石蒜碱、力可拉敏和加兰他敏以及虎杖中大黄素和白藜芦醇在MAE提取过程中的扩散系数D，与溶剂加热回流法（SRE）比较，引入增强因子y，表征了微波对溶质分子扩散传质的影响及其对不同基盾药材作用的差异。

英文摘要：

A mathematical model of microwave-assisted extraction （MAE） kinetics based on Fick＇s second diffusion law was established for Chinese traditional medicine. The model proposed has been verified via using experimental data from MAE of Lycoris radiata and Rhizma Polygoni Cuspidati at different levels of tempera-ture, extraction time and granularity. The simulated results show that the values calculated by the model were consistent with the experimental data. The diffusion coefficients of the effective constituents in Lycoris radiata and Rhizma Polygoni Cuspidati were calculated according to the kinetic modeling method and compared reasonably with those obtained with SRE method, and intensifying factor was introduced as a parameter to esti- mate the microwave effects on the extraction process of the constituents with MAE and the interaction difference between the different matrices of Chinese traditional medicine was revealed successfully.