中文摘要：

目的：观察降钙素基因相关肽（calcitonin-gene-relatedpeptide，CGRP）样阳性终末在中央杏仁核（centralnucleusofamygdala，CeA）内形成的突触的超微结构。方法：应用免疫荧光组织化学和包埋前免疫电镜等方法，观察CGRP样阳性终末在CeA内所形成的突触分布形式及结构特点。结果：CGRP样阳性终末在中央杏仁核内可以与细胞体、树突干和树突棘等结构形成突触；轴-体突触几乎全为对称性突触，而轴-树突触和轴-棘突触则多为非对称性突触。在所有的非对称性突触里，轴-树突触占84．9％，而轴．棘突触占15．1％。CGRP样阳性轴-树的突触后致密带的平均长度为（790．77±313．55）nm，而轴-棘突触的突触后致密带的平均长度为（723．34±357．20）nm，两者之间没有显著性差异。结论：CGPR样阳性的兴奋性突触尤其是轴．树突触在伤害性信息传递以及痛相关情绪的产生中发挥了重要作用。

英文摘要：

Objective： To observe synaptic ultrastructure of calcitonin-gene-related peptide （CGRP）-like rive （LI） axonal terminals in the central nucleus of amygdala （CeA）. Methods： Immunofluorescence and pre-embedding electronic microscopy were employed to detect the classification and structural features of synapses made by CGRP-LI ax- onal terminals in the CeA. Results： CGRP-LI terminals were observed to make synapses on the soma of neurons, dendrit- ic shafts and spines. Almost all the axo-soma synapses were symmetrical; However, most of the axo-dendritic shaft and axo-spine synapses were asymmetrical. In all asymmetrical synapses, the ratio of axo-dendritic shaft synapses were 84.9% , and axo-spine synapses 15.1%. The average length of postsynaptie density （PSD） of axo-dendritic shaft synap- ses was 790.77 ± 313.55 nm, whereas of axo-spine synapses 723.34 ± 357.20 nm. There was no significant difference of PSD length between two types of synapses. Conclusion： The CGRP-LI axo-dendritic shaft synapses play important roles in the transmission of nocieeption and pain-related abnormal emotional responses.