干眼病是眼科常见的眼表疾病,其发病机制复杂,目前尚无一种理想的动物模型能较好地模拟出干眼病发病缓慢、反复发生、逐渐恶化的特点。研究认为,炎症是干眼病发的主要因素。本文主要对Th1细胞和Th17细胞及其相关细胞因子在干眼病发病中作用做简要概述。
· Dry eye disease is a common ocular surface disease in ophthalmology and its complex pathogenesis makes no animal model could perfectly mimic the characteristic of dry eye disease which is chronic, repeated and worse. Studies showed inflammation plays an important role in the development of dry eye disease and we gave an overview of Thl cell and Th17 cell in the pathogenesis of dry eye disease in this review.