位置:成果数据库 > 期刊 > 期刊详情页
Advances in genomic selection in domestic animals
  • 期刊名称:Chinese Science Bulletin
  • 时间:0
  • 页码:2655-2663
  • 语言:英文
  • 分类:S813.9[农业科学—畜牧学;农业科学—畜牧兽医] Q78[生物学—分子生物学]
  • 作者机构:[1]Key Laboratory of Animal Genetics and Breeding of the Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
  • 相关基金:This work was supported by the National ‘948' Project (2011-G2A, 2010-C14), the Key Development of New Transgenic Breeds Project (2009ZX08009-146B), the National Natural Science Foundation of China (30800776), and the Innovation Fund for Graduate Student of China Agricultural University.
  • 相关项目:利用单倍型信息进行畜禽基因精细定位
中文摘要:

Genomic 选择(GS ) 是一个帮助标记的选择方法,盖住整个染色体的高密度标记同时在被使用因为经由 genomic 的单个基因评估估计了繁殖价值(GEBV ) 。GS 能增加选择的精确性,弄短由在生活的早阶段选择个人的产生间隔,并且加速基因进步。与染色体 SNP (单个核苷酸多型性) 为家畜削的高密度全部的可获得性, GS 正在重塑引起系统的常规动物。在许多国家, GS 在乳牛为公牛选择正在成为主要基因评估方法, GS 可以完全很快代替传统的基因评估系统。在最近的年里, GS 在繁殖的动物,植物和水产养殖成为了一个重要研究话题,许多令人激动的结果被报导了。在这篇论文,为在家畜获得 GEBV,影响 GEBV 的精确性的因素,和 GS 的实现的当前的地位的方法被考察。与在家畜的 GS 有关的一些未解决的问题也被讨论。

英文摘要:

Genomic selection (GS) is a marker-assisted selection method, in which high density markers covering the whole genome are used simultaneously for individual genetic evaluation via genomic estimated breeding values (GEBVs). GS can increase the ac- curacy of selection, shorten the generation interval by selecting individuals at the early stage of life, and accelerate genetic pro- gress. With the availability of high density whole genome SNP (single nucleotide polymorphism) chips for livestock, GS is re- shaping the conventional animal breeding systems. In many countries, GS is becoming the major genetic evaluation method for bull selection in dairy cattle and GS may soon completely replace the traditional genetic evaluation system. In recent years, GS has become an important research topic in animal, plant and aquiculture breeding and many exciting results have been reported. In this paper, the methods for obtaining GEBVs, factors affecting the accuracy of GEBVs, and the current status of implementation of GS in livestock are reviewed. Some unresolved issues related to GS in livestock are also discussed.

同期刊论文项目
同项目期刊论文