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Role of acoustic interface layer during high intensity focused ultrasound therapeutics
  • ISSN号:1000-3630
  • 期刊名称:《声学技术》
  • 时间:0
  • 分类:Q62[生物学—生物物理学]
  • 作者机构:[1]Sate Key Laboratory of Medical Ultrasound Engineering Co-founded by Chongqing andMinistry of Science and Technology, Institute of Ultrasound Engineering, Department of Biomedical Engineering, Chongqing Medical University, Chongqing 400016, China
  • 相关基金:Supported by the Development Plan for Innovation Teams of Ministry of Education (2005-33). the National Natural Science Foundation of China (30471653). and tile Natural Science Foundation of Chongqing (2006BA5020)
中文摘要:

在接口层被磁性的 nano 粒子在鸡蛋白人幽灵模仿以后,高紧张在一样的剂量集中了超声(HIFU ) 被介绍在不同深度散发幽灵吹声学的接口层模仿点暴露。当声学的焦点的区域(AFR ) 与接口层是靠近的时,结果证明生物焦点的区域(BFR ) 的卷被扩大。这意味着磁性的 nano 粒子提高了 HIFU 的治疗学的效率。当从接口层的 AFR 的距离是 10 公里时, BFR 的尺寸和形状与控制组的那些是类似的,但是在接口的更大的损害,为处理有害,被观察。当到接口层的 AFR 的距离增加了到 30 公里时, BFR 的尺寸和形状也类似于控制组的那些。当接口层的厚度减少了时,改进的用途减少了。为改进的实用程序的处理和减少的安全区域的连续增加与接口层的厚度的消退一起被观察

英文摘要:

After interface layer was simulated by the magnetic nano-particles in the egg white phantom, high intensity focused ultrasound (HIFU) at the same dosage was introduced to radiate the phantom in different depths to blow the acoustic interface layer to mimic "point" exposure. The results showed that the volumes of biological focal region (BFR) were enlarged when the acoustic focal region (AFR) is close with interface layer. This meant that the magnetic nano-particles enhanced the therapeutic efficiency of HIFU. When the distance of the AFR from the interface layer was 10 mm, the size and shape of the BFR were similar with those of the control group, but a larger lesion at the interface, which was harmful for treatment, was observed. When the distance of the AFR to the interface layer increased to 30 mm, the size and shape of the BFR were also similar to those of the control group. When the thickness of the interface layer diminished, the utility of enhancement decreased. Continuous increase of the safe area for treatment and decrease of the utility of enhancement were observed along with the abatement of the thickness of the interface layer

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期刊信息
  • 《声学技术》
  • 北大核心期刊(2014版)
  • 主管单位:中国科学院
  • 主办单位:中科院声学所东海研究站 同济大学声学研究所 上海市声学学会 上海船舶电子设备研究所
  • 主编:张叔英
  • 地址:上海市嘉定工业区新徕路399号
  • 邮编:201815
  • 邮箱:sxjs@vip.163.com
  • 电话:021-67084688-2101 64174105
  • 国际标准刊号:ISSN:1000-3630
  • 国内统一刊号:ISSN:31-1449/TB
  • 邮发代号:
  • 获奖情况:
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  • 被引量:5693