中文摘要：

以对苯二酚为原料经羟基的甲基化、傅克酰基化、肟化、肟基还原、酮胺氢化5步反应合成了盐酸甲氧明，中间体和目标产物经核磁共振氢谱、红外光谱及元素分析仪确证了其化学结构，总收率为37．6％．与传统盐酸甲氧明工艺相比，该工艺反应条件温和、简便、经济、产率高及对环境友好．

英文摘要：

Methoxamine hydrochloride was synthesized from p-dihydroxybenzene by O-methylatlon, Friedel-Crafts acylation, oximation reaction, oxime reduction and keto-amine hydrogenation reactions. All intermediates and products were characterized by IR, lH NMR spectra and elemental analysis. The total yield was 37.6%. Compared to the traditional synthetic procedures of methoxamine hydrochloride, the procedures were temperate, convenient, economical, high-yielding and environment-friendly.