中文摘要：

基于碱基组合在DNA序列中出现的频率，构造11个物种的p-globin基因第一个外显子的编码序列的频率矩阵．借助矩阵2-范数对11个物种进行相似性比较，并结合柱状图对物种之间的相似性进行分析．研究结果表明：所构造的DNA序列频率矩阵不仅能够反映出DNA序列中碱基及碱基组合的含量分布，而且能够显示出序列碱基突变的情况．

英文摘要：

The frequency matrix of coding sequence of the first exon of β-globin gene of eleven species was proposed based on the frequencies of nucleotide combinations in the DNA sequences. The similarity of eleven species was compared with the aid of 2-norm of matrix. Moreover, the similarity analysis was spread among species with column graphs. The results showed that the frequency matrix of DNA sequences not only could reflect the content distribution of nucleotides and nucleotide combinations in DNA sequences, but also could display the mutations of sequences nucleotides.