中文摘要：

目的探讨在超声声场作用下,微泡是否可能有助于更多地向局部输送氧。方法依据菲克第一定律、玻意耳定律及道尔顿气体分压定律,建立超声声场作用下的微泡气体交换方程和计算机模拟程序。结果超声辐照加速了微泡内外的气体交换,促进了微泡内O2的快速向外释放。理论分析说明,在超声声场中,微泡的体积收缩和膨胀将加速其内外气体压力的变化和气体交换。结论在高频率交变压力的作用下,超声将加速平衡微泡与周围组织的O2/CO2分压的差异,有助于向局部输送更多氧。

英文摘要：

Objective To investigate the theory of ultrasound-enhanced oxygen delivery by microbuhbles. Methods Ac- cording to the Fick theory, Boyle law and Dalton law, the mathematical model for O~ exchange in micorobubbles under ul- trasound field was made. Results Under ultrasound field, gas exchange was enhanced and oxygen delivery was acceler- ated. Theoretical analysis showed that the expansion and contraction of mierobubbles would accelerate the change of gas pressure and gas exchange. Conclusion Ultrasound may accelerate the balance of O2/CO2 between microbubbles and its surrounding tissues under the alternate pressure, therefore increasing 02 exchange to surrounding tissue.