中文摘要：

基于直流绝缘式介电泳技术和数值模拟方法,设计了一种二维微扩锯齿状微通道,实现对直径分别为4,8,12,16和20μm的聚苯乙烯微粒进行多目标同时分离。通过分析介电泳力对微粒运动轨迹的影响,并与平行锯齿状微通道中颗粒在运动过程中的受力及分离效果进行对比,结果表明微扩锯齿状微通道能够实现多种不同直径微粒的完全分离,且分离效果优于平行锯齿状微通道,更有利于多目标的高通量分离。通过进一步调节微扩通道扩展角、电压以及管道齿数对微扩通道进行优化,使其分离效果与性价比达到最优。此项研究为同时进行多目标微粒的高精度、高通量、连续分离提供新思路和理论支持。

英文摘要：

Based on the DC insulated dielectrophoretic technology and numerical simulation method,a two-dimensional gradually expanded sawtooth microchannel was designed.The multitarget separation of polystyrene particles with diameters of 4,8,12,16,20μm were carried out simultaneously.The influences of the dielectrophoretic force on the movement trace of particles were analyzed,and the forces in the movement process and separation effect of the particles in the parallel sawtooth microchannel were compared with those of the two-dimensional gradually expanded sawtooth microchannel.The results show that the particles with different diameters are completely separated in the gradually expanded sawtooth microchannel and the separation effect in the gradually expanded sawtooth microchannel is superior to that in the parallel sawtooth microchannel,which is more favorable to the multi-target separation with higher throughput.Furthermore,the expansion angle,voltage and sawtooth number of the gradually expanded sawtooth microchannel were adjusted to optimize the microchannel and achieve the optimal separation effect and performance.The investigation provides a new idea and theoretical support for high resolution,high throughput and continuous separation of multi-taget particles.