中文摘要：

目的：研究簕欓花椒（Zanthoxylum avicennae）叶挥发油的化学成分及其抗菌和抗肿瘤活性。方法：用水蒸气蒸馏法从簕欓花椒叶中提取挥发油,用气相色谱-质谱联用技术对其挥发油成分进行分析。结果：从挥发油中鉴定出72种物质,占总成分的98.15%,含量较高的组分为芳樟醇（24.36%）、β-榄香烯（12.03%）、（E）-2-己烯-1-醇（11.73%）、石竹烯氧化物（10.84%）等。簕欓花椒叶挥发油对实验菌株均具有一定的抗菌活性;对四种肿瘤细胞株都具有一定的抑制活性,其中对白血病细胞K-562的抑制活性最强,IC50值为1.76μg/mL。结论：簕欓花椒挥发油具有多种活性成分,为进一步研究其药理作用提供了科学依据。

英文摘要：

Objective：To study the chemical constituents,antimicrobial activity and antitumor activity of the essential oil from Zanthoxylum avicennae.Methods： The essential oil from the leaves of Zanthoxylum avicennae was extracted by steam distillation.The components of the essential oil were separated and identified by GC-MS.Results： 72 components were identified and accounted for 98.15% of the all peak area.The essential oil exhibited strong antitumor activity against K-562 human tumor cell lines with IC50 of 1.76 μg/mL.It also exhibited moderate antimicrobial activity against three bacteria.Conclusion： The essential oil of Zanthoxylum avicennae contains various active constituents.This result provides scientific reference for the pharmacological further research of Zanthoxylum avicennae.