中文摘要：

近年来,药物在生态系统中的富集已成为国内外研究的热点。环境药理学是一门深入探讨环境中药物来源及其转化的新兴学科。研究发现,药物及其活性代谢物可通过制药工业、医院、农业生产等多个途径进入环境。环境中的药物不仅可影响生态系统导致细菌产生耐药,还能影响生物膜菌群平衡。环境中的药物还可通过诱导基因表观遗传学的变化,从而使机体易受疾病的侵害。内分泌干扰物的富集则可干扰人类生殖系统的发育和功能。我国对环境药物产生污染的关注刚刚起步,环境药理学的学科发展有助于阐明药物与环境的交互作用,有利于我国公众健康和食品安全。

英文摘要：

In recent years,researches on drugs concentrated in the ecosystem have become a hot topic. Environmental pharmacology is a new subject studying the source and fate of drugs in the environment. It is found that a lot of pharmaceuticals and pharmaceutically active compounds are released into the environment by the pharmaceutical industry,hospitals and agricultured activities.Drugs in the environment not only affect the ecosystem,which leads to bacterial resistance,but also affect the balance of flora in the biofilm. Furthermore,such drugs may induce epigenetic changes,which may leave to the body vulnerable to diseases. The enrichment of endocrine disruptors can interfere with the growth and function of the human reproductive system. China is becoming concerned about environmental drugs. The development of environmental pharmacology can help clarify the interactions between drugs and the environment while contributing to public health and food safety in China.