中文摘要：

目的观察回药爱康方对C57小鼠Lewis肺癌细胞转移的影响,并检测各组小鼠瘤组织bcl-2的表达。方法将55只C57荷瘤小鼠随机分为荷瘤模型组,环磷酰胺（CTX）组,回药爱康方低剂量组、回药爱康方低剂量加化疗组、回药爱康方高剂量加化疗组。治疗后,观察各组小鼠肺表面转移灶和bcl-2蛋白的表达情况。结果 （1）肺转移灶的变化：与荷瘤模型组比较,其余各组小鼠肺转移灶差异有统计学意义（P〈0.05）。（2）bcl-2表达情况：与荷瘤模型组比较,其余各组bcl-2的表达差异有统计学意义（P〈0.01）。结论回药爱康方有抗小鼠肺癌转移和降低bcl-2表达的作用。

英文摘要：

Objective To observe metastatic effect of Hui medicine Aikangfang in C57 mice Lewis lung cancer cells and test bcl-2 expression in each mice tumor tissue.Methods Fifty-five tumor-bearing mice were randomly divided into model group,chemotherapy（CTX） group,low-dose group,low-dose with chemotherapy group and high-dose with chemotherapy group.After treatment,observing the lung surfaces metastasis and bcl-2 protein expressions of each mouse.Results（1） Lung metastases changes：compared with tumor-bearing model,the more than mice lung metastases is statistically significant difference（P〈0.05）.（2） bcl-2 expression：compared with tumor-bearing model,the more than bcl-2 expression is statistically significant difference（P〈0.01）.Conclusion Hui medicine Aikangfang can resist lung cancer metastasis in mice and reduce bcl-2 expression.