中文摘要：

将鲫鱼分别暴露于浓度为0、0．1、0．5、1．0、5．0和10．0mg·L^-1的阿特拉津溶液中，在染毒后的第3、6、10、14、19和24d对1．0和10．0mg·L^-1两个浓度组的鲫鱼进行取样；在实验结束时（24d）对所有浓度组进行取样，分别测定其肝脏、肾脏和肌肉中SOD活性，研究在不同作用时间和不同暴露浓度下，阿特拉津对鲫鱼肝脏、肾脏和肌肉SOD活性的影响。结果表明，阿特拉津能使鲫鱼肝脏、肾脏和肌肉SOD活性产生显著变化。在染毒后的第24d，各浓度组肝脏SOD活性均受到抑制，肾脏SOD活性均受到诱导，肌肉SOD活性在低浓度下受抑制，高浓度下被诱导；且在本实验所设浓度范围内，阿特拉津与肝脏SOD活性之间存在剂量-效应关系，与肾脏SOD活性在1．0—10．0mg·L^-1范围内存在剂量-效应关系。在14—24d内，阿特拉津与肌肉SOD活性之间存在时间-效应关系，与肝脏和肾脏SOD活性之间在任何时间范围内都不存在明显的时间-效应关系，但在整个实验期内，1．0和10．0mg·L^-1两个暴露浓度对同一器官SOD活性的影响具有相同的变化趋势。

英文摘要：

Atrazine is one of the most commonly used herbicides in the world. Due to its long persistence, it is present in many surface and ground waters, contaminating nontarget organisms such as fish and threatening drinking water of human beings. The experiment was performed to research the effects of atrazine on superoxide dismutase （SOD） activities in Carassius auratus. Groups offish were exposed to atrazine at concentrations of 0, 0.1, 0.5, 1.0, 5.0 and 10.0 mg·L^-1, respectively. The SOD activities in liver, kidney and muscle exposing to 1.0 and 10.0 mg·L^-1 were measured after 3, 6, 10, 14, 19 and 24 d of the experiment, respectively, to study the time-response relationships between atrazine and SOD activities in these organs. And at the end of the experiment （24 days）, SOD activities in the three organs exposing to all the concentrations were evaluated to research the dose-response relationships between atrazine and SOD activities in these organs. SOD activities in liver, kidney and muscle changed significantly with atrazine. At the end of the experiment, SOD activities in liver were inhibited but induced in kidney at all the concentrations of atrazine, while, SOD activities in muscle were inhibited at low concentrations and induced at high concentrations. There existed dose-response relationships between atrazine and hepatic SOD activities at all the concentrations, and renal SOD activities at 1.0- 10.0 mg·L^-1, respectively. The time-response relationship between atrazine and muscular SOD activities existed at 14-24 d. There were no time-response relationships between atrazine and hepatic or renal SOD activities at any time. During the whole experimental period, 1.0 and 10.0 mg·L^-1 atrazine had similar influences on SOD activities in the same organ.