脂氧素(1ipoxins,LXs)为花生四烯酸代谢产物,是体内最重要的内源性脂质抗炎促消退介质之一。近年来,有关LXs合成途径、生物学效应及其在某些肝脏疾病中的作用等方面的研究均有许多进展。为此,该文就相关内容作一综述。
Lipoxins (LXs), metabolites of arachidonic acid, are one of the most important endogenous lipid mediators which initiate inhibition inflammatory reaction as well as promote extinction of inflammation resolution. Nowadays, many advancements have been achieved in the research of their biosynthetic pathways, biological func-tions and effects in hepatic diseases. This article will review the progress in the related research.