中文摘要：

目的：为基本药物供应保障体系的优化提供策略。方法：通过交易费用理论和大数据技术方面的理论研究。分析信息质量引致的基本药物供应保障体系交易费用问题。结果：网上集中采购信息系统没有控制原料药企业、生产企业和配送企业．基层医疗机构和患者之间的交易关系，导致信息碎片化；政府间信息不对称及对市场的不适当干预，增加了政府型交易费用：信息共享不充分、交易的复杂化增加了市场型交易费用。结论：运用交易费用理论界定政府和市场的功能，优化交易结构：采用大数据技术获取全局。陡信息，减轻信息碎片化。

英文摘要：

Objective： To present the optimized strategy for the optimization of essential medicine＇s supply security system. Methods： Through the theoretical analysis of transaction cost theory and big data technology, it analyzed the transaction cost problem induced by the intbrmation quality. Results： The reason for information fragmentation was the online centralized purchasing system did not control the transaction relationship among raw material pharmaceutical company, pharmaceutical manufacturer, distribution enterprise, primary care institution and patients. The government transaction cost was increased by the information asymmetry between government and the inappropriate intervention in the market. The market transaction cost was increased by the unshared information and the transaction complexity. Conclusion： The transaction cost theory helped to define the function of government and market to optimize the transaction structure. The big data helped to access the overall situation information so as to lessen the information fragmentation.