中文摘要：

提出了一种简便易行的对磁性纳米粒子表面进行氨基化的方法.首先使用化学共沉淀法合成了粒径为10nm左右的Fe3O4纳米粒子,然后用阿仑膦酸钠对其表面进行修饰,使其表面具有了功能化的氨基.利用透射电子显微镜（TEM）、X射线衍射（XRD）、振动样品磁强计（VSM）、动态光散射（DLS）仪、热重分析（TGA）仪、傅里叶变换红外（FT-IR）光谱仪、X射线光电子能谱（XPS）仪等对其进行表征.结果显示磁性纳米粒子表面被成功地修饰了一层双膦酸分子.所制备的纳米粒子可在pH=6.3稳定存在4周以上.

英文摘要：

We propose a convenient method to synthesize surface amino-coated magnetic nanoparticles.Fe3O4 nanoparticles with a grain diameter of about 10 nm were synthesized by the chemical co-precipitation of ferrous chloride and ferric chloride.The obtained superparamagnetic nanoparticles were surface-modified with alendronate to introduce an amino group onto their surfaces.The particles were characterized by transmission electron microscopy （TEM）,X-ray diffraction （XRD）,vibrating sample magnetometry （VSM）,dynamic light scattering （DLS）,thermogravimetric analysis （TGA）,Fourier transform infrared （FT-IR） spectroscopy,and X-ray photoelectron spectroscopy （XPS）.The data showed that alendronate was successfully linked to the SPM nanoparticles.These particles are stable for more than 4 weeks without precipitation at pH= 6.3.