中文摘要：

目的：研究新疆维吾尔族人群环氧化物水解酶（EPHX2）基因rs751141多态性与原发性高血压的关系。方法：通过流行病学调查获得新疆维吾尔族原发性高血压患者302例（高血压组），健康对照组323例，采用TaqMan探针法分析EPHX2基因rs751141多态性的基因型。结果：高血压组与对照组EPHX2基因rs751141G／A多态性差异无统计学意义。结论：EPHX2基因rs751141G／A多态性与新疆维吾尔族原发性高血压无相关性。

英文摘要：

Objective：To study the relationship between rs751141 polymorphisms in EPHX2 gene and essential hypertension in Uygur population in Xinjiang. Method： Through epidemiological survey in Xinjiang Uygur popula- tion, 302 cases were as essential hypertension group and 323 cases as normal control group. TaqMan probe meth- od was used to analysis the rs751141 polymorphism genotype in EPHX2 gene. Result：The rs751141 G/A polymorphism in EPHX2 gene had no,significant difference between two groups. Conclusion：The essential hypertension in Uygur in Xinjiang is not associated with rs751141 G/A polymorphism of EPHX2 gene.