中文摘要：

The function of the transplanted heart will be affected by acute allograft rejection,chronic rejection,high blood pressure and so on,which may induce the reconstruction of the left ventricle and the increase of left ventricular mass(LVM),and eventually lead to left ventricular hypertrophy that will significantly affect the prognosis of heart transplantation(HT).The purpose of this study was to dynamically monitor the changes of left ventricular geometric patterns after HT using two-dimensional echocardiography and to understand the remodeling process and its possible influencing factors.The left ventricular internal diameter,interventricular septal wall thickness,posterior wall thickness at end diastole were measured and the relative wall thickness(RWT),left ventricular mass,left ventricular mass index were calculated respectively in 34 HT patients and 34 healthy volunteers by two-dimensional echocardiography.The type of left ventricular geometry was identified based on the echocardiographic determination of LVM index(LVMI)and RWT.The HT patients were divided into three groups according to the time length after surgery:A(3 months postoperatively),B(6 months postoperatively)and C(12 months postoperatively).We compared the parameters of left ventricle between HT group and normal control group,and explored the risk factors causing the increase of LVM.The results showed that 4 patients(16%)in group A had concentric remodeling.Nine patients(34.62%)in group B had reconstruction,including 5 cases of concentric remodeling,2 cases of concentric hypertrophy and 2 cases of eccentric hypertrophy.The hypertrophy incidence rate was 15.4%in group B.15 patients(62.5%)had reconstruction in group C,including 9 cases of concentric remodeling,5 cases of concentric hypertrophy,and 1 case of eccentric hypertrophy.The prevalence of hypertrophy was 25%.Multivariate analysis showed that hypertension and acute rejection history were the risk factors that resulted in left ventricular hypertrophy.It is concluded that the left ventricular re

英文摘要：

The function of the transplanted heart will be affected by acute allograft rejection, chronic rejection, high blood pressure and so on, which may induce the reconstruction of the left ventricle and the increase of left ventricular mass （LVM）, and eventually lead to left ventricular hypertrophy that will significantly affect the prognosis of heart transplantation （HT）. The purpose of this study was to dy- namically monitor the changes of left ventricular geometric patterns after HT using two-dimensional echocardiography and to understand the remodeling process and its possible influencing factors. The left ventricular internal diameter, interventricular septal wall thickness, posterior wall thickness at end dias- tole were measured and the relative wall thickness （RWT）, left ventricular mass, left ventricular mass index were calculated respectively in 34 HT patients and 34 healthy volunteers by two-dimensional echocardiography. The type of left ventricular geometry was identified based on the echocardiographic determination of LVM index （LVMI） and RWT. The HT patients were divided into three groups ac- cording to the time length after surgery： A （3 months postoperatively）, B （6 months postoperatively） and C （12 months postoperatively）. We compared the parameters of left ventricle between HT group and normal control group, and explored the risk factors causing the increase of LVM. The results showed that 4 patients （16%） in group A had concentric remodeling. Nine patients （34.62%） in group B had re- construction, including 5 cases of concentric remodeling, 2 cases of concentric hypertrophy and 2 cases of eccentric hypertrophy. The hypertrophy incidence rate was 15.4% in group B. 15 patients （62.5%） had reconstruction in group C, including 9 cases of concentric remodeling, 5 cases of concentric hyper- trophy, and 1 case of eccentric hypertrophy. The prevalence of hypertrophy was 25%. Multivariate analysis showed that hypertension and acute rejection history were the risk fac