目的:评价针灸治疗溃疡性结肠炎的有效性和安全性。方法:检索近10年针灸干预溃疡性结肠炎的随机对照试验或临床对照试验,并对文献结果进行Meta分析。结果:共11篇临床研究文献入选。对11项研究结果进行异质性检验,结果x^2=8.55,P=0.67,采用固定效应模型进行统计分析,合并后OR=3.82,95%可信区间为2.65—5.52,菱形位于中间线的右侧,经Z检验,Z=7.14,P〈0.01,试验组和对照组疗效比较差异有非常显著性意义,即针灸治疗组疗效明显优于对照组,痊愈率高于对照组。结论:针灸治疗溃疡性结肠炎疗效优于西药,且副作用少,具有安全性。
Objective To assess the effectiveness and safety of acupuncture and moxibustion for treatment of ulcerative colitis. Methods Randomized controlled trials or clinical controlled trials of acupuncture and moxibustion for interfere of ulcerative colitis in recent 10 years were reviewed and Meta-analysis was made for the literature resuits. Results Altogether 11 papers of clinical study were enrolled. Heterogeneous tests were conducted for the results of the 11 studies, as a result, x^2=8.55, P=0.67. The fixed effect model was used for statistical analysis, after combination OR= 3.82, confidence interval of 95% was 2.65-5.52. The rhombus was located at the right side of the medium line. After Z test, Z=7.14, P〈0.01, the therapeutic effect and the cured rate in the treatment group were significantly higher than those of the control group. Conclusion The therapeutic effect of acupuncture and moxibustion on ulcerative colitis is superior to that of western medicine with safety and less adverse reactions.