星形细胞上调基因1(AEG-1)是一种癌基因,研究表明它在多种肿瘤的发生发展中发挥着重要的功能。本文就AEG-1在消化系统肿瘤的细胞增殖、侵袭转移、血管生成及化疗耐药等方面的研究进展做一综述。
Astrocyte elevated gene-1(AEG-1)is an oncogene.It has been demonstrated that AEG-1 associated with the generation and development of many cancers.In this paper,we will review recent pregress about AEG-1 and proliferation,invasion,migration,angiogenesis and chemotherapy resistance of human digestive system tumor.