大鼠心肌缺血/再灌注损伤模型是研究冠心病缺血再灌注及抗心律失常药物最常用的灌注损伤模型。总结实验过程中的经验及教训,对提高大鼠心肌缺血/再灌注损伤模型成功率的方法进行探讨。
Rat myocardial ischemia/reperfusion in situ is the most frequently used animal model for studing coronary artery disease,ischemic preconditioning and selecting antiarrhythmic drugs. In this paper,we reported some methods to improve tech-niques for making myocardial reperfusion injury rat model.