位置：成果数据库 > 期刊 > 期刊详情页
P-选择素Lectin结构域稳定性的模拟预测
  • ISSN号：1000-6737
  • 期刊名称：《生物物理学报》
  • 时间：0
  • 分类：Q51[生物学—生物化学]
  • 作者机构：[1]中国科学院力学研究所,国家微重力实验室/生物力学与生物工程中心
  • 相关基金：国家自然科学基金项目(10702075,30730032);科技部“蛋白质科学”国家重大研究计划(2006CB910303);科技部863项目(2007AA02Z306);中国科学院知识创新工程项目(KJCX2-YW-L08)的支持
作者： 吕守芹[1], 龙勉[1]
关键词： 选择素, 分子动力学模拟
中文摘要：

选择素(selectin)与其配体间相互作用介导的细胞粘附在炎症级联反应、肿瘤转移和淋巴细胞归巢等病理、生理过程中起重要作用[1]。X-ray衍射发现P-选择素的最小功

同期刊论文项目
受体-配体结合动力学及其外力调控
期刊论文 38 会议论文 11 著作 3
P-选择素EGF结构域功能的模拟预测
期刊论文 5
同项目期刊论文
Residue identification in molecular aqueous pathway determines water permeability of rice PIPs
细胞 -分子生物力学研究进展
Low Spring Constant Regulates P-selectin-PSGL-1 Bond Rupture
Effects of oriented substrates on cell morphology, the cell cycle, and the cytoskeleton in Ros 17/2.
Developing a microfluidic-based system to quantify cell capture efficiency
Shear- and stretch-induced dissociation of P-selectin/PSGL-1 complex using molecular dynamics simula
Dynamics of morphological changes for mitochondrial fission and fusion
Identification of a residue in helix 2 of rice plasma membrane intrinsic proteins that influences wa
Molecular modeling and affinity determination of ScFv antibody: Proper linker peptide enhances its a
Visualization of allostery in P-selectin lectin domain using MD simulations
Fluid dynamics analysis of a micropatterned cell bioreactor
Probe stiffness regulates receptor-ligand bond lifetime under forces
A Novel Counter Sheet-flow Sandwich Cell Culture System to Unravel Cellular Responses in Space
2整合素介导的人中性粒细胞在ICAM-1表面的铺展动力学
Conformational stability analyses of alpha subunit I domain of LFA-1 and Mac-1
Determination of binding kinetics of ?2-integrin and ICAM-1 interactions in melanoma adhesion to leu
Advances in Experiments and Modeling in Micro- and Nano-Biomechanics——A Mini Review
流体剪切力作用下无间隙连接成骨细胞陈列的钙响应
Spreading of human neutrophils onto ICAM-1-immobilized substrate under shear flow
Two-dimensional kinetics of ?2-integrin and ICAM-1 bindings between neutrophils and melanoma cells i
Mechanics of single mitochondrion is correlated to mitochondrial functionality.
Measuring binding kinetics of surface-bound molecules using surface plasmon resonance technique
Low Spring Constant Regulates P-selectin-PSGL-1 Bond Rupture
Quantifying cell binding kinetics mediated by surface-bound blood type B antigen to immobilized anti
Editorial: Special Issue: Experiments and modeling in micro- and nano-biomechanics
中国微重力流体科学的空间实验研究
Surface-bound selectin-ligand binding is regulated by carrier diffusion
IL-8-induced L-selectin shedding regulates its binding kinetics to PSGL-1
微模式化基底上大鼠骨髓间充质干细胞的增殖、分化和迁移
IL-8刺激L-选择素水解断裂对细胞膜拓扑结构和刚度的影响
Space experimental studies of microgravity fluid science in China
Parametric analysis for monitoring 2D kinetics of receptor-ligand binding
分子动力学模拟与分子生物力学
Mechanokinetics of receptor-ligand interactions in cell adhesion
Spring constant regulate selectin-ligand bond dissociation
Quantifying cell binding kinetics mediated by surface-bound blood type B antigen to immobilized antibodies
Distinct Kinetics Features of LFA-1 and Mac-1 in Neutrophil Activation
期刊信息
  • 《生物物理学报》
  • 北大核心期刊（2011版）
  • 主管单位:中国科协
  • 主办单位:中国生物物理学会
  • 主编：沈恂
  • 地址：北京朝阳区大屯路15号生物物理研究所内
  • 邮编：100101
  • 邮箱：acta@sun5.ibp.ac.cn
  • 电话：010-64888458
  • 国际标准刊号：ISSN：1000-6737
  • 国内统一刊号：ISSN：11-1992/Q
  • 邮发代号:
  • 获奖情况:
  • 二次获得中国科协优秀科技期刊奖
  • 国内外数据库收录:
  • 美国化学文摘（网络版）,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,中国北大核心期刊（2004版）,中国北大核心期刊（2008版）,中国北大核心期刊（2011版）,中国北大核心期刊（2014版）,中国北大核心期刊（2000版）
  • 被引量:7189