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Low Spring Constant Regulates P-selectin-PSGL-1 Bond Rupture
  • 时间：0
  • 分类：Q51[生物学—生物化学]
  • 相关基金：Supported by National Natural Science Foundation of China grants 30730032 and 10702075;National Key Basic Research Foundation of China grant 2006CB910303;National High Technology Research and Development Program of China grant 2007AA02Z306;Chinese Academy of Sciences grant KJCX2-YW-L08
  • 相关项目：受体-配体结合动力学及其外力调控
关键词： Selectin-ligand, BONDS, RUPTURE, Spring, constant, Optical, TRAP
中文摘要：

Forced dissociation of selectin-ligand bonds is crucial to such biological processes as leukocyte recruitment, thrombosis formation, as well as tumor metastasis. While forced

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