中文摘要：

金黄色葡萄球菌（Staphylococcus aureus）,简称金葡菌,是重要的人类病原菌,是世界范围内细菌感染的主要原因。金葡菌通过产生多种毒素如p-v杀白细胞素（panton-valentine leukocidin,PVL）,引起固有免疫细胞如巨噬细胞、中性粒细胞释放多种促炎因子导致机体炎症损伤,并诱导这些细胞发生凋亡坏死,而高效地逃避固有免疫系统的识别和消除,引起严重的感染性疾病。本文综述了金葡菌产生的alpha溶血素、PVL、可溶性调控蛋白（Phenol-soluble Modulin,PSM）和Staphopain的促炎机制及对宿主固有免疫细胞的杀伤作用,为临床治疗金葡菌引起的感染提供参考。

英文摘要：

Staphylococcus aureus is an important human pathogen,the primary cause of bacterial infectious diseases in the world. S. aureus evokes intrinsic immunocytes such as macrophages,and neutrophils to release various toxins and p-v leukocidin（ panton-valetine leukocidin,PVL） and cause inflammation damage of the organism,promote these cells to undergo apoptosis,and high-efficiently escape the identification and elimination of the innate immune system,eliciting serious infectious disease. In this paper α-haemolysin,PVL,phenol-soluble modulin（ PSM）,and proinflammatory mechanisms of staphopain produced by S. aureus has the killing effects on the host immunocytes was reviewed,providing a theoretical basis for clinical treatment against infection caused by S. aureus.