中文摘要：

目的：观察不同干预措施下大鼠胸导管淋巴液量及其组胺、5-羟色胺等物质含量的变化，初步探讨淋巴系统在针灸疗效中的作用。方法：雄性Wistar大鼠随机分为对照组、针刺组、温针灸组，每组15只。采用显微外科技术复制大鼠胸导管淋巴瘘模型。针刺、温针灸大鼠双侧“足三里”穴30min，观察大鼠胸导管淋巴液量的变化情况，双抗体夹心ELISA法检测各组大鼠淋巴液中组胺、5-羟色胺浓度。结果：针刺组、温针灸组较对照组明显增加胸导管淋巴液量（P〈0．05），但各组间淋巴液中组胺、5-羟色胺浓度变化的差异无统计学意义（P〉0．05）。结论：针灸刺激可以增加胸导管淋巴回流，淋巴系统可能在针灸起效中发挥作用。

英文摘要：

Objective To observe the changes of thoracic duct lymph volume and the contents of histamine （HA）, 5- hydroxytryptamine （5-HT）, etc. in the lymph after acupuncture or thermal acupuncture interventions, in order to investigate the effect of lymphatic system in transmitting acupuncture and moxibustion signals. Methods A total of 45 male Wistar rats were randomly divided into control group, acupuncture group, and thermal acupuncture （acupuncture with the needle warmed by burning moxa） group （n = 15/ group）： The rat thoracic duct lymphatic fistula model was replicated. Acupuncture or thermal acupuncture was applied to ＂Zusanli＂ （ST 36）, and the changes of thoracic duct lymph volume and the concentrations of HA, 5-HT in the lymph were observed. Results Compared with the control group, the thoracic duct lymph volume in acupuncture group and thermal acupuncture group were obviously increased （ P〈0.05 ）, while the concentrations of lymph HA and 5-HT in both acupuncture and thermal acupuncture groups had no significant changes （P〉0.05）. Conclusion Both acupuncture and thermal acupuncture in- terventions can increase the thoracic duct lymph volume, but have no effects on lymph HA and 5-HT contents in normal rats.