Variant angina (VA) has been described the clinical entity whereby a sudden intense,spontaneous and reversible vasoconstriction of a coronary artery branch,subsequently resulted in subtotal or total occlusion during the duration of attack or provocative test.It is used to appear frequently at rest in the absence of any augment of myocardial oxygen demand and associated with STsegment elevation on electrocardiography rather than with the usual ST-segment depression during the attack of exertional angina.Although the development of VA has been suggested to be associated with endothelial dysfunction and primary hyper-reactivity of vascular smooth muscle cells (VSMCs) triggered by some stimulating factors,such as smoking,the exact mechanism for this unique coronary disorder is largely unknown.Keywords:vasospastic angina; dyslipidemia; therapy