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超急性和急性脑梗死的扩散张量成像研究
  • ISSN号:1006-9011
  • 期刊名称:《医学影像学杂志》
  • 时间:0
  • 分类:R743.33[医药卫生—神经病学与精神病学;医药卫生—临床医学] R445.2[医药卫生—影像医学与核医学;医药卫生—诊断学;医药卫生—临床医学]
  • 作者机构:[1]浙江省人民医院放射科浙江杭州310014
  • 相关基金:基金项目:本课题受浙江省医药卫生科学研究资助(项目编号:2006A04)
中文摘要:

目的:探讨扩散张量成像(DTI)技术在超急性和急性脑梗死患者中的临床应用价值。方法:对19例超急性脑梗死、22例急性脑梗死患者行常规颅脑MRI及DTI检查。测量梗死灶中心区、边缘区及对侧镜像区的FA、DCavg值,并得到DWI图、DCavg图、FA图、彩色编码FA图及皮质脊髓束图。结果:DWI图、DCavg图、FA图及彩色编码FA图可清楚显示超急性和急性脑梗死病灶。超急性和急性脑梗死组梗死灶中心区FA值分别为(0.481,0.284)×10-4mm2/s,边缘区FA值分别为(0.473,0.306)×10-4mm2/s,急性脑梗死组梗死灶中心区、边缘区FA值与超急性脑梗死组之间差异有统计学意义。超急性和急性脑梗死组梗死灶中心区DCavg值分别为(4.207,4.924)×10-4mm2/s,边缘区DCavg值分别为(5.805,5.420)×10-4mm2/s,急性脑梗死组梗死灶中心区、边缘区与超急性脑梗死组DCavg值之间差异亦有统计学意义。白质纤维束三维重建显示皮质脊髓束为无受累、部分受累、完全受累,其临床肌力分别表现为无减退、治疗后肌力恢复或大部分恢复、无恢复。结论:DTI技术对超急性和急性脑梗死的诊断、治疗及判断预后具有重要的价值。

英文摘要:

Objective:To explore the clinical value of diffusion tensor imaging (DTI) in hyperacute and acute cerebral infarction. Methods: Conventional MRI and DTI were performed in 19 patients with hyperacute cerebral infarction and 22 ones with acute cerebral in- farction. FA and DCavg value of eentral, peripheral part of lesions and control regions were measured. DWI map, DCavg map, FA map, color-coded FA map and corticospinal tract (CST) were obtained. Results: DW/map, DCavg map, FA map, color-coded FA map showed lesions of hyperacute and acute cerebral infarction obviously. FA value of eentral parts in hyperacute and acute cerebral infarction were (0.481, 0.284) ~ 10-4nan2/s, respectively. FA value of peripheral parts in hyperacute and acute cerebral infarction were (0.473, 0.306) × 10-4mm2/s, respectivdy. Difference of FA value in central and peripheral parts of lesions between hyperaeute and acute cere- bral infarction were significant. DCavg value of central parts in hyperacute and acute cerebral infarction were (4. 207,4. 924) × 10-4 mm2/s, respectively. DCavg value of peripheral parts in hyperacute and acute cerebral infarction were (5. 805,5.420)× 10-4mm2/s, respectively. Difference of DCavg value in central and peripheral parts of lesions between hyperacute and acute cerebral infarction were significant. CST showed intact, partial disrupted and mostly disrupted, whose myodynamia was normal, recovered after therapy, and not recovered, respectively. Conclusion: DTI has great value for diagnosis, clinical management and prognosis of hyperacute and acute cerebral infarction.

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期刊信息
  • 《医学影像学杂志》
  • 中国科技核心期刊
  • 主管单位:山东省卫生厅
  • 主办单位:山东省医学影像学研究会 山东省医学影像学研究所
  • 主编:赵斌
  • 地址:山东省济南市经四纬九路37号
  • 邮编:250021
  • 邮箱:xyxxzz@126.com
  • 电话:0531-87920996 87031478
  • 国际标准刊号:ISSN:1006-9011
  • 国内统一刊号:ISSN:37-1426/R
  • 邮发代号:24-134
  • 获奖情况:
  • 2007年山东省优秀科技期刊
  • 国内外数据库收录:
  • 俄罗斯文摘杂志,波兰哥白尼索引,美国剑桥科学文摘,英国科学文摘数据库,中国中国科技核心期刊
  • 被引量:28228