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中文摘要：
基于多个结构域联合作用导致蛋白质间相互作用的假设，提出了一种预测蛋白质间相互作用的新方法。使用支持向量机分析结构域组合对序列的氨基酸理化性质得到其序列特征值，同时采用统计分析的方法获取其频率特征值，最后通过融合上述两种特征估计该结构域组合间发生相互作用的可能性，并以此预测蛋白质间相互作用关系。该方法能够预测所有结构域组合间相互作用关系，且对于蛋白质相互作用关系有着较好的预测效果。
英文摘要：
In this paper, we propose a new, method to predict the interaction possibility of protein pairs. The method is mainly based on SVM algorithm using amino acid sequence information of domain combination pairs, and statistical calculating method as a supplementary. Thus, we can evaluate the interacting probability of all the possible domain combination pairs of each protein pair and preferable effect is obtained in the prediction of protein- protein interaction.
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