中文摘要：

包含羟基磷灰石（HA）和磷酸三钙（TCP）的双相磷酸钙陶瓷（BCP）由于其具有良好的降解性能和良好的骨诱导性被看作是骨替代和修复的首选材料。BCP陶瓷的降解性能主要受相成份、孔隙率、材料微观形貌的影响。通过化学共沉淀法制得了成份为60/40（HA/TCP）的双相BCP粉体,通过双氧水发泡法制得了孔隙率分别为40%、60%和80%的多孔双相BCP陶瓷。选用Tris缓冲液浸泡的方法测试材料的体外降解行为。结果显示,孔隙率的改变有效地调控了BCP陶瓷的降解性能。随孔隙率的增加材料的溶出显著加快。高孔隙率材料的快速降解,在体系中释放出相对较高的钙、磷浓度,这可能是其高生物活性的重要影响因素。

英文摘要：

The degradation rate of BCP can be controlled by tri-calcium phosphate（TCP）content,porosity and micro-morphology.In this paper we regulated the degradation rate of BCP by changing the porosity.Through H2O2 foaming method we successfully obtained the BCP with porosity of 40%,60%,80%.Degradation test was performed by immersing the materials in Tris buffer and testing the released calcium（Ca）and phosphorus （P）concentrations.The degradation test shows that dissolution rate of BCP can be regulated effectively through the change of porosity.The enhanced bioactivity of BCP with higher porosity might due to both the structure and the increased Ca and P ions releasing.