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不同状态下电针大鼠心包经原穴大陵效应特征的观察
  • ISSN号:1664-3849
  • 期刊名称:世界科学技术-中医药现代化
  • 时间:2014.7.20
  • 页码:1597-1601
  • 分类:R246.1[医药卫生—针灸推拿学;医药卫生—中医临床基础;医药卫生—中医学]
  • 作者机构:[1]南京中医药大学国家重点省部共建针药结合实验室,南京210029
  • 相关基金:科学技术部国家重点研究发展计划“973计划”项目(2011CB5050206):针刺对功能性肠病双向调节与自主神经功能的关系,负责人:徐斌; 国家自然科学基委金青年基金项目(81202744):小脑顶核-下丘脑外侧区-自主神经通路介导穴位配伍效应,负责人:余芝; 中国中医科学院自主选题项目(ZZKF06003):小脑-下丘脑-自主神经通路介导穴位效应的研究,负责人:徐斌; 江苏省教育厅高校自然科学研究项目(11KJB360008):A1受体及TRPV1蛋白在电针上巨虚治疗内脏痛敏的作用研究,负责人:余芝; 江苏省教育厅特色优势学科资助:中医学科,负责人:吴勉华; 江苏省教育厅高校研究生创新课题:肾上腺素β受体介导电针不同腧穴双向调节心功能的研究,负责人:汪娅莉
  • 相关项目:小脑顶核-下丘脑外侧区-自主神经通路介导穴位配伍效应的研究
中文摘要:

目的:观察不同状态下电针心包经原穴大陵对心内压的影响,探索针灸的效应特征。方法:通过右颈总动脉插管至左心室的方法记录左心室内压。以心内压为指标,分别在正常生理、异丙肾上腺素和心得安等状态下观察电针"大陵"对大鼠左心室内压的影响。结果:以针刺的即刻效应来说,对正常大鼠电针大陵可以明显的兴奋心内压;在静脉给予心得安和异丙肾上腺素状态下,电针大陵无明显反应。而从针刺的效应方向上看,正常情况下电针大陵具有兴奋效应;心得安状态下具有抑制效应;异丙肾上腺素状态下效应不定。结论:据腧穴的特异性定向作用,大陵可以兴奋心内压。

英文摘要:

This article was aimed to observe the intracardiac (EA) on yuan-source point of PC7-Daling and to explore the pressure under different states by electric acupuncture acupuncture effect features. Catheterization was applied through the right common carotid artery to the left ventricle in order to record the left intraventricular pressure. The intracardiac pressure was used as an indicator. The effects of EA on PC7-Daling to the left intraventricular pressure of rats were observed under the states of normal physiology, isoproterenol and propranolol, respectively. The results showed that for the immediate effects of acupuncture, EA on PC7-Daling can obviously excited the intracardiac pressure of normal rats. Under the state of intravenous application of propranolol and isoproterenol, no obvious reac tions during EA on PC7-Daling. From the effects of acupuncture, under normal conditions, EA on PC7-Daling had excitatory effect; under propranolol state, it had inhibitory effects; and the effect of isoproterenol state was variable. It was concluded that according to the specificity of acupoint effect, PC7-Daling can excite intracardiac pressure.

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