中文摘要：

人口流行病学证据表明, 炎症性肠病的发病率与寄生虫感染率呈负相关, 提示寄生虫感染具有治疗炎症性肠病的潜力。目前对待寄生虫的视角, 逐渐从消除寄生虫, 转向到利用寄生虫或其排泄分泌物开发安全、有效的炎症性肠病疗法。本文就近年来运用寄生虫模型治疗炎症性肠病的效果及机制的研究进展做一综述。

英文摘要：

Epidemiological evidence has shown that the morbidity of inflammatory bowel disease in human is negatively correlated with the infection rate of parasites, indicating a therapeutic potential of parasite infection for inflammatory bowel disease. There have been explorations on a switch from parasite elimination to using their excretory-secretory products to develop safe and effective inflammatory bowel disease therapies. This review summarizes the therapeutic effectiveness of parasite infection models in the treatment of inflammatory bowel disease and the underlying mechanisms.