胃食管反流与哮喘的发生有着密切的联系。实验证实迷走神经在食管-支气管哮喘的发生中起一定的作用,而胆碱能神经递质和胆碱受体可能在胃食管反流性哮喘的发病机制中占有重要的地位,提示抗胆碱能药物在胃食管反流性哮喘的治疗过程中具有潜在的应用前景。
Gastroesophageal reflux(GER) has a close association with asthma through vagal nerve.Cholinergic nerve and cholinergic receptors might play an important role in the development of GER-induced asthma,indicating that anti-cholinergic drugs may have therapatic potential in the treatment of asthma induced by gastroesophageal reflux.