中文摘要：

先将合成的纳米镍修饰裸玻碳电极,再在修饰电极表面热聚合一种以甲基丙烯酸为功能单体、马来松香丙烯酸乙二醇酯为交联剂、纳米氧化铜掺杂的异戊巴比妥分子印迹敏感膜。研究了印迹电极的最佳成膜条件及其最佳实验条件。采用循环伏安法（CV）和电化学交流阻抗法（EIS）对印迹传感器的电化学性能进行表征。使用红外光谱和扫描电镜分别探究此印迹敏感膜的结构及表面形貌。在最佳实验条件下,以K3Fe（CN）6为分子探针的差分脉冲伏安法（DPV）峰电流响应值与异戊巴比妥的浓度在6.5×10-8~1.8×10-4mol/L范围内呈现良好的线性关系（线性相关系数R=0.9986）;检出限为1.1×10-9mol/L（S/N=3）。传感器能用于猪肉中残留异戊巴比妥的检测,加标回收率在96.5%~103.2%之间。

英文摘要：

Uniform nickel nanoparticles were synthesized and modified on the surface of glassy carbon electrode. The molecularly imprinted polymer （MIP） films doped with CuO nanoparticle for the determination of amobarbitalwere prepared by thermal polymerization method with methacrylic acid as functional monomers, and ethylene glycol maleic rosinate acrylate as a cross linking agent. The optimum experimental conditions were explored. The electrochemical properties of the nano - doped sensor were investigated using cyclic vohammetry （CV） and electrochemical impedance spectroscopy （EIS）. The structure and morphologies of the imprinted films were characterized using infrared （IR） spectroscopy and scanning electron microscopy （SEM）. Under the optimal conditions, the relative redox peak currents of hexacyanoferrate showed a linear dependence on the amobarbital concentration in the range from 6. 5 × 10 -5 to 1.8 × 10 -4 mol/L （ linear regression coefficient R = 0.9986） with a detection limit of 1.1 × 10-9 mol/L （S/N = 3）. The prepared sensor was successfully applied for the determination of amobarbital in pork samples and the recovery ranged from 96.5% to 103.2%.