中文摘要：

为了提高苯巴比妥分子印迹传感器的灵敏度，以甲基丙烯酸为功能单体，马来松香丙烯酸乙二醇酯为交联剂，热聚合了一种纳米氧化铜掺杂的苯巴比妥分子印迹传感器。分别采用循环伏安法（CV）、电化学交流阻抗法（EIS）、差分脉冲伏安法（DPV）、计时电流法（CA）对这种印迹传感器的电化学性能进行了研究。分别采用红外光谱、扫描电镜对此印迹传感器的结构及形貌进行了表征。结果表明，以铁氰化钾为分子探针的间接检测中，铁氰化钾的峰电流值与苯巴比妥的浓度在1.2×10^-7-1.5×10^-4mol/L范围内呈现良好的线性关系（线性相关系数R=0.9984），检出限（S/N=3）为8.2×10^-9mol/L。将此印迹传感器用于实际应用，回收率在96.5%-103.0%之间。

英文摘要：

To improve the sensitivity,a CuO nanoparticle doped in molecularly imprinted polymer（MIP）film for the determination of phenobarbital was prepared by using methacrylic acid as functional monomers, ethylene glycol maleic rosinate acrylate as a cross linking agent by thermal polymerization method. The electrochemical properties of the nano-doped sensor were investigated using cyclic voltammetry （ CV ） , differential pulse voltammetry （ DPV ） , electrochemical impedance spectroscopy （ EIS ） and chrono-amperometry （ CA） . The chemical structures and morphologies of the imprinted films were characterized using Fourier transform infrared spectroscopy and scanning electron microscopy. The results indicated that the sensors response value of peak current showed a linear dependence on the phenobarbital concentration in the ranges of 1. 2 × 10^-7-1. 5 × 10^-4 mol/L of phenobarbital. （ Linear regression coefficient=0. 9984 ） with the detection limit （ S/N=3 ） of 8. 2 × 10^-9 mmol/L. The prepared sensor was successfully applied to the determination of phenobarbital in practical samples with recovery ranging from 96 . 5% to 103 . 0%.